The Middle East respiratory syndrome (MERS) coronavirus is a viral respiratory disease first reported in Saudi Arabia about a year ago. The disease is caused by a coronavirus called MERS-CoV. In general, a coronavirus is an enveloped virus with a positive RNA genome and a nucleocapsid of helical symmetry. Typically, human coronaviruses are known to cause upper respiratory tract infections. While there is no cure yet, the Centers for Disease Control and Prevention is currently researching the development of a vaccine. Some symptoms of this respiratory infection include fever, cough, kidney failure, pneumonia, and shortness of breath. Unfortunately, about half of the known cases of MERS worldwide have resulted in death. Research has indicated that the virus spreads in the air through respiratory droplets, which makes doctors extremely sensitive. As the disease spreads, scientists and experts fear that the virus could mutate and become more transmissible. In recent news, scientific investigators confirmed the presence of the MERS coronavirus in a camel, which belonged to a Saudi man who was also ill with the new virus. This discovery turned out to be crucial because it now provides crucial evidence about animal hosts and transmission of the virus. First, the discovery adds credibility to the common theory that the virus originates in bats and typically spreads to humans through camels. That's because in most early cases of MERS, the first patient to get sick had contact with a sick, infected camel. The virus usually spreads gradually from person to person after first appearing in a community, but medical experts have been baffled in terms of the original origin of the virus... half of the paper... and the genetic makeup of MERS The virus must be evaluated to determine the method of replication and transmission of the disease. Simply put, viruses are packages of DNA or RNA surrounded by a protein shell called a capsid. To replicate, viruses rely on the processes of transcription (DNA to RNA) and translation (mRNA to protein). Because viruses cannot reproduce, they must infect a host cell to replicate. Eventually, viruses infect cells by entering the host cell or by injecting its DNA or RNA directly into the cell. Therefore, to limit the spread of the disease and develop an immunization, biologists and disease experts must determine the genetic sequence and infection cycle of the MERS coronavirus. All in all, the scientific relevance in relation to the MERS epidemic is evident and scientific research is needed to decode this esoteric disease.
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