Antimicrobial and Antioxidant Characteristics of Nutmeg IntroductionHydroxyl radical, hydrogen peroxide, singlet oxygen, superoxide anion and free radicals are made up of reactive oxygen species. These reactive species will cause damage to biological molecules. Damaged biomolecules could cause certain diseases or lead to the worsening of existing diseases. Free radicals are reactive ions that can cause the progression of diseases such as diabetes, immunosuppression, metabolic damage, atherosclerosis, ischemic heart disease, Alzheimer's disease, aging and Parkinson's disease. Diseases resulting from oxidative stress could be prevented by exogenous antioxidants such as tocopherols, flavonoids, vitamin C, carotenoids and various phenolic compounds. Some commonly used synthetic antioxidants are butylated hydroxyanisole, butylated hydroxytoluene (BHT). Natural antioxidants in plants can prevent disease by reducing oxidative damage created by biomacromolecules. Various harmful pathogens cause different diseases to humans. When human defense mechanisms are not sufficient to fight pathogens, some chemotherapy drugs are introduced. The casual use of these drugs has led to the development of drug-resistant strains. There is therefore an extreme need to create alternatives to synthetic drugs. The answer to this problem can emerge from the use of aromatic herbs and spices. Spices and herbs have antimicrobial and antioxidant properties. Nutmeg: Nutmeg is the dried seed of Myristica fragrans Houtt. It has anti-tumor, anti-inflammatory and anti-diarrheal properties. Nutmeg also acts as a memory enhancer and aphrodisiac. This study focuses on investigating…halfway through the article…reverses the process and thus the rate of antioxidation by nutmeg extract is inversely related to the oxidation of beta-carotene. Acetone extract showed this activity as 74.36+/-1.94% and ethanol extract as 38.47+/-1.31%. The BHT showed this activity as 94.9+/-1.03%. Antimicrobial Activity of Extracts In this study, it was demonstrated that nutmeg extracts exhibited antimicrobial activity against pathogenic bacteria and fungi. GC-MS of Acetone Extract The acetone extract of nutmeg seeds consisted of the chemicals such as sabinene, beta-pinene, myristicin, terpinen-4-ol, limonene, gamma-terpinene, p-menth-2- en-1-ol, elemicin, isoeugenol, p-menth-2-en-1-ol, myrcene, alpha-phellandrene, terpinolene, lonalool and p-cymene. In conclusion, the present study elaborated the antimicrobial and antioxidant properties of different nutmeg extracts.
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