Contraceptive drugs are used to prevent pregnancy. They work by changing the hormonal environment of the female reproductive tract so that an egg is not produced, either by killing sperm or by preventing the fertilized egg from implanting in the endometrium. There are many drugs that can do this. Some include oral contraceptives, transdermal patches, and even implants. Pregnancy occurs when an egg is fertilized by a male's sperm. In females, the anterior pituitary gland produces follicle-stimulating hormone (FSH), which stimulates the follicle in the ovary to form a mature egg and also to secrete estradiol which thickens the endometrium. Subsequently, the anterior pituitary gland also produces luteinizing hormone (LH), which causes the follicle to release the mature egg. This process is known as ovulation. Subsequently, LH causes what remains of the follicle (corpus luteum) to release estradiol and progesterone. If the egg is fertilized, progesterone and estradiol continue to be secreted. If the egg is not fertilized, the corpus luteum disintegrates and progesterone secretion stops. This causes the uterine lining to disintegrate and shed in the process known as menstruation (Turley, 2010, p. 209). Humans have been using different forms of contraception since ancient times. In ancient Egypt, women used a combination of cotton, dates, honey, and acacia as a suppository to prevent pregnancy. It has now been proven that fermented acacia actually has a spermicidal effect. There are also references in both the Quran and the Bible to coitus interruptus, which refers to the method of abstinence. Between 1914 and 1921, activist Margaret Sanger coined the term “birth control” and opened the first birth control clinic. In 1951, Mexican chemist Carl Djerassi formulated a pill by synthesizing hormones from sweet potatoes. Even though the pill worked on a chemical level, it could not be tested or distributed. In 1960, the FDA finally approved the pill as a contraceptive. During these years, numerous improvements and modifications have been made to the original drug that have reduced negative side effects. In 2000, the Equal Employment Opportunity Commission determined that contraception should be covered by employer-provided health insurance. It is important to note that contraceptive drugs do not protect against sexually transmitted diseases. There are still problems with the adverse effects of drugs such as YAZ, Ocella and Yasmin (Nikolchev, 2010), which are all oral contraceptives. Oral contraceptives are probably the largest class of contraceptives and are divided into three groups: monophasic, biphasic and triphasic.