What this will do is allow the electron transport chain to continue but it will stop or slow down the production of ATP, this will cause all the useful energy to be lost as heat. The drug DNP sends protons across membranes in oxidative phosphorylation and prevents electrons from releasing energy, thus blocking ATP synthesis. DNP will lead to weight gain because when our bodies produce less ATP the only way to compensate for this loss is to speed up our metabolism, as a result more fats and carbohydrates will be used as energy instead of being stored as fat. This all seems good at first glance, but when you look closer you will see how dangerous this drug can be. By stopping the production of ATP and causing all this energy to be lost as heat, you can cause your body temperature to rise. Body temperature can rise so much that it causes hyperthermia; when body temperature rises well above normal and can cause death. In the article 2,4-Dinitrophenol by Simon Cotton, many deaths are mentioned. People range from being body builders to regular people trying to lose weight. In any case, the reason for the death was the particular person who had taken an overdose and hyperthermia was caused (Cotton 2015). This drug could be used but only if you have very careful supervision and have the right dosage, however the problem is that people's tolerance to DNP can vary greatly, so even with this supervision it is still possible to overdose if your tolerance is lower to expected