Introduction: Onchocerciasis is a disease of public health and socio-economic importance in Ethiopia. Onchocerciasis, commonly known as “river blindness,” is caused by the parasitic worm Onchocerca volvulus which is transmitted to humans through the bite of infected black flies. The transmitted worm larvae develop into adults and lodge in the fibrous nodules of the human body and produce microfilariae. Prolonged infection of the parasitic worm can lead to blindness and depigmentation of the skin. Onchocerciasis mainly affects the southwestern region of Ethiopia, Africa and the Americas (World Health Organization, 2006) and the Life cycle and mode of entry: The life cycle of O. volvulus is complex and depends on significant from the black fly. The life cycle includes many steps that could be interrupted to avoid contracting the disease. The life cycle is as follows;1. During a bite, an infected black fly (genus Simulium) introduces third-stage larvae to human skin, where they enter the bite wound2. In skin tissues, larvae mature into adults, which commonly exist in nodules in skin connective tissues3. Adults can live in the nodules for about 15 years. Some nodules may contain numerous male and female worms.4. A black fly ingests microfilariae during a blood meal.5. After ingestion, microfilariae migrate from the blackfly midgut through the hemocoel to the thoracic muscles.6. There the microfilariae develop into first instar larvae7. And subsequently into infective larvae of the third stage.8. The third instar infective larvae migrate towards the proboscis9 of the black fly. And it can infect another human when the fly consumes another blood meal. Effects and Current Treatments: The worm O. volvulus has multi...... half of article ......vention, 2013). Another preventative measure volunteers can use is to cover their skin; wearing long sleeved shirts and long trousers is vital, this will prevent the black fly from biting the individual. If volunteers use these small but significant prevention measures, they will be able to avoid being bitten and infected. Conclusion: In conclusion, the eradication of onchocerciasis in Ethiopia is highly possible and probable with the help of volunteer groups like this to help and assist small villages and communities by educating them on how to avoid getting infected. The group of volunteers will be sufficiently able to avoid infection if some simple steps are followed and special attention is paid. It can be predicted that with the education of communities across Ethiopia the eradication of the disease will be highly likely.